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KMID : 0665220120250041027
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Korean Journal of Food and Nutrition
2012 Volume.25 No. 4 p.1027 ~ p.1032
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Absorption Evaluation of Enteric Coated Capsules Containing Omega 3 Fatty Acids
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Park Eu-Deum
Park Yoo-Heon
Park Sung-Sun
Suh Hyung-Joo
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Abstract
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We investigate the changes of fatty acids in blood for an evaluation of the effects of soft and enteric coated capsules containing omega 3 fatty acids. Fish oil, which contained 62.87 g/100 g of sum of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), was used as nutracueticals for omega 3 fatty acids. Lipid releasing amount in soft capsule was 70% in stomach condition. However, there was 10% of releasing amount of lipid observed in enteric coated capsule in stomach condition. In intestinal condition, 50% of lipid releasing amount in enteric coated capsule showed until 6 hr, but soft capsule until 90 min. EPA and DHA contents in soft capsule administration showed higher level than those in enteric coated capsule until 8 hr. However, the administration of enteric coated capsule showed higher level of EPA and DHA in blood after 8 hr. After 24 hr, mono-, poly-unsaturated and saturated fatty acids contents with enteric coated capsule showed higher level than those with soft capsule. The enteric coated capsule containing omega 3 fatty acids was expected to sustain omega 3 fatty acids.
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KEYWORD
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enteric coated capsule, omega 3 fatty acid, EPA, DHA
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